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Naltrexone for Weight Loss
A commercially available Weight Loss Product, Contrave, that consists of Naltrexone & Bupropion, has been used by many to lose weight. In a study, patients experienced clinically significant weight loss when combined with a diet and exercise program and also decreased body weight in patients with diabetes. People are hesitant of the weight loss solution because Bupropion is an antidepressant. Those people can contact ICP Folsom to get Naltrexone for weight loss without the antidepressant Bupropion.
We spent a lot of the last 2 years talking about Low Dose Naltrexone (LDN) and Town & Country Compounding, being the global experts in Naltrexone, has had many prescribers requesting LDN. In fact, Town & Country Compounding has a protocol that they use. You can contact the pharmacy or have the doctor contact us. This is often used when patients do not want to use the antidepressant drug combination bup-ntx that is commercially available.
Weight Loss & Menopause
Does menopause make us fat?
Fat seems to shift towards the midsection & the scale moves in the wrong direction even though your diet and exercise regimen has not changed. Sound familiar? Many women going through perimenopause and menopause struggle with their weight. If this describes you, do not think you are alone!
Why Do We Gain Weight?
Aging is a big factor. Lifestyles change as we age. We lose muscle (therefore burn less fat) gain fat more easily, sit more, and have less physical activity as we age.
We can’t discount menopause as a factor. The loss of estrogen leads to a shift of fat to the midsection. During the menopause transition, night sweats, sleep disturbance, and problems with mood are common and may affect a woman’s ability to adhere to a healthy diet and regular exercise program
Although estrogen used for management of menopause symptoms is not a weight-loss drug, it improves body composition by reducing abdominal fat.
“As if the hot flashes, mood swings, night sweats and sexual challenges weren’t enough, now you can add weight gain to the menopausal whammy.
That’s right. In case you hadn’t noticed (fat chance!), women tend to gain about 10 to 15 pounds on average—from 3 to 30 pounds is the typical range—during and after menopause. And because our entire metabolic mechanism is different now, that weight is blessedly hard to take off.”
Low Dose Naltrexone (LDN)
Read about the mechanism in which low dose naltrexone LDN works to reduce inflammation.
Abstract Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells. These effects may be unique to low dosages of naltrexone and appear to be entirely independent from naltrexone’s better-known activity on opioid receptors. As a daily oral therapy, LDN is inexpensive and well-tolerated. Despite initial promise of efficacy, the use of LDN for chronic disorders is still highly experimental. Published trials have low sample sizes, and few replications have been performed. We cover the typical usage of LDN in clinical trials, caveats to using the medication, and recommendations for future research and clinical work. LDN may represent one of the first glial cell modulators to be used for the management of chronic pain disorders.
What is Low Dose Naltrexone (LDN)?
Naltrexone belongs to a class of drugs known as opioid antagonists. Naltrexone blocks opiate drugs from binding to the opioid receptors, which can result in increased endorphin and enkephalin release. Therefore, this results in reduced: 1. signaling and release of inflammatory substances, 2. nerve cell inflammation and 3. autoimmune mediators.